705Correlation of Radiologic Tests in the Diagnosis of Brucellosis with Osteoarticular Involvement

Correlation of Radiologic Tests in the Diagnosis of Brucellosis with Osteoarticular Involvement Background. The most common complication of brucellosis is musculoskeletal system involvement. Bone and joint involvement in brucellosis may present as mainly sacroiliitis and spondylitis. In this study, we aimed to evaluate the correlation of plain X-rays, bone scintigraphy, and contrast-enhanced magnetic resonance imaging in the diagnosis of osteoarticular involvement of brucellosis. Methods. Patients older than 18 years old, who followed up, diagnosed with brucellosis disease and decided to get treatment in Cukurova University, Faculty of Medicine, Infectious Diseases and Clinical Microbiology clinic and outpatient clinic between May 2009 and November 2010 were included in the patient group. Results. Average age of 86 patients with brucellosis diagnosis were 40.86 ± 18.4 and there were 38 (44,2%) males and 48 (55,8%) females in this group. Spondylitis and sacroiliitis have been described in the same ratio, 22.1% (n = 19). Sacroiliitis were unilateral in 13 and bilateral in six patients. Sacroiliac involvement was detected in 28.9% of men and 16.6% of women (p = 0,270). Eight patients (42.1%) had both sacroiliitis and spondylitis. Pathological involvement was determined in Tc99m bone scintigraphy in only three of 19 patients (15.8%) with sacroiliitis in plain X-rays. One patient with normal bone scintigraphy had bilateral sacroiliitis in MRI. Two patients with normal bone scintigraphy had bilateral spondylitis in MRI. Seven patients had findings of spondylodisciitis in both bone scintigraphy and MRI. Conclusion. Our findings suggest that there may be inconsistency between plain X-ray, bone scintigraphy and MRI. Sensitivity of bone scintigraphy is low at brucellar sacroiliitis and false negative results were seen when compared to MRI in spondiliitis cases. As a result, spondylitis can be accidentally underdiagnosed by the bone scintigraphy, which is used for screening osteoarticular involvement. Disclosures. All authors: No reported disclosures.